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rPeptide/Zileuton/N-3023-2/50 mg
来自 : 发布时间:2024-05-06
Description Reversible inhibitor of 5-Lipoxygenase (IC50 = 500 nM in RBL-1 cells and 300 nM rat PMNLs)1. It also inhibited leukotriene B4 biosynthesis (IC50s = 400nM rat PMNL, 400nM human PMNL)1. Zileuton suppressed prostaglandin biosynthesis via interference with arachidonic acid release in macrophages independent of 5-LO inhibition (IC50 = 13 μM PGE2 inhibition in LPS-stimulated whole blood)2. Restores memory impairments and reverses amyloid and tau pathology in an Alzheimer’s mouse model3. Molecular Mass 236.3 Purity >98%

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发布于 : 2024-05-06 阅读()
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