肽/钙调素，小麦（普通小麦），生物素化/C-1008-1/
商品编号：
C-1008-1
品牌：
rPeptide Inc.
市场价：
¥5300.00
美元价：
2915.00
产品分类：
其它动物抗原
公司分类：
Other_animal_antigens
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Source
Isolatedfromwheatgerm
Description
ThepresenceofCysteine26inWheatgerm(Triticumaestivum)calmodulin(CaM)makesituniquevis-a-vismammaliancalmodulin.IncontrasttomammalianCaMs,whichlackcysteine,thispreparationisidealforapplicationsrequiringbothcalmodulinactivationandresiduespecifictagging.Mono-taggedBiotinylatedlabeledwheatgermcalmodulinatpositionCysteine26isusefulforproteinarrayapplicationsforthedetectionofcalmodulinbindingproteins(CBPs),Westernblotsandotherapplicationsrequiringaconvenientandsuperiorfluorescentlylabeledcalmodulin.Calmodulin(CaM)isaubiquitous,calcium-bindingproteinthatbindsandregulatesamultitudeofproteintargets,manyofwhichareinvolvedintheAlzheimer"sandtheParkinson"spathways1,4.CaMhasamolecularweightofabout17kDa,containing148aminoacids,andpIof3.9.CaMischaracterizedbytwodomains,connectedbyanalpha-helixchain.Eachdomainhasthecapacitytobindtwocalciumions.BindingCa2+ionscausesaconformationalchangeinCaM,makingitavailableforinteractionwithtargetproteins.Hence,CaMfunctionsasanintracellularcalciumionbridgetomediatecellularreactionsandrespondsappropriatelytocalciumionconcentration.InAlzheimer"sdisease(AD),irregularcalciumhomeostasisseemstotriggerCaManditsbindingproteins,toenhanceplaqueformationandneurofibrillarydegeneration,whichresultsincelldeath1.TheincreasedcytosoliclevelsofCa2+inADneuronspromotesCaMbindingandregulationofavailableCa2+/CaM-dependentCaM-bindingproteins,associatedwithamyloidbeta(Ab)formation.Inaddition,theincreasedlevelofCa2+triggersCalmodulintoactivatecalcium/CaM-dependentkinaseIIandprecedeneurofibrillarytangleformation2,4.InParkinson"sdisease(PD),Calmodulinhasbeenfoundtointeract,inacalciumdependentmanner,withAlpha-Synuclein,whichisassociatedwiththeprogressionofPD.CaMwasidentifiedasoneofthesynuclein-interactingproteinsthatregulatesynucleinconformation3.
MolecularMass
16,750Da
Purity
>95%bySDS-PAGEstainedwithCoomassiebluehavingasinglebandatapproximately17kDa;Actualmolecularweightis16,750Da.
品牌介绍
rPeptide (www.rpeptide.com) 是一家生物化学公司，坐落于美国乔治亚州，与雅典毗邻。该公司研发试剂是市场领跑者，主要 产品涉及领域为老年性痴呆症与帕金森综合症研究使用的重组蛋白，重组多肽，抗体以及试剂等等。该公司提供一系列外包服务，从分子生物学，蛋白表达与蛋白纯 化到13C与15N 统一标记蛋白与多肽。同时， rPeptide 技术平台可解决可溶性多肽/蛋白（例如：β-淀粉样蛋白、廋蛋白、前胰岛素）在大肠杆菌中表达等历史性难题。
产品清单：
商品名称 商品货号 商品品牌
Beta-Amyloid (1-40), Mouse, Rat A-1007-1 rPeptide
Beta-Amyloid (1-40), Starter Kit A-1150-1 rPeptide
Beta-Amyloid (1-40), Starter Kit A-1150-2 rPeptide
Beta-Amyloid (1-40), Ultra Pure, HCl A-1156-1 rPeptide
Beta-Amyloid (1-40), Ultra Pure, HCl A-1156-2 rPeptide
Beta-Amyloid (1-40), Ultra Pure, HFIP A-1153-1 rPeptide
Beta-Amyloid (1-40), Ultra Pure, HFIP A-1153-2 rPeptide
Beta-Amyloid (1-40), Ultra Pure, NaOH A-1155-1 rPeptide
Beta-Amyloid (1-40), Ultra Pure, NaOH A-1155-2 rPeptide
Beta-Amyloid (1-40), Ultra Pure, TFA A-1001-1 rPeptide
Beta-Amyloid (1-40), Ultra Pure, TFA A-1001-2 rPeptide
Beta-Amyloid (1-40, D23N) A-1013-1 rPeptide
Beta-Amyloid (1-40, D23N) A-1013-2 rPeptide
Beta-Amyloid (1-40, F4W) A-1011-1 rPeptide
Beta-Amyloid (1-40, F4W) A-1011-2 rPeptide
Beta-Amyloid (1-40, Scrambled) A-1003-1 rPeptide
Beta-Amyloid (1-40, Scrambled) A-1003-2 rPeptide
Beta-Amyloid (1-40, Y10W) A-1012-1 rPeptide
Beta-Amyloid (1-40, Y10W) A-1012-2 rPeptide
Beta-Amyloid (1-42), Mouse, Rat A-1008-1 rPeptide
Beta-Amyloid (1-42), Mouse, Rat A-1008-2 rPeptide
Beta-Amyloid (1-42), Starter Kit A-1160-1 rPeptide
Beta-Amyloid (1-42), Starter Kit A-1160-2 rPeptide
Beta-Amyloid (1-42), Ultra Pure, HCl A-1166-1 rPeptide
Beta-Amyloid (1-42), Ultra Pure, HCl A-1166-2 rPeptide
Beta-Amyloid (1-42), Ultra Pure, HFIP A-1163-1 rPeptide
Beta-Amyloid (1-42), Ultra Pure, HFIP A-1163-2 rPeptide
Beta-Amyloid (1-42), Ultra Pure, NaOH A-1165-1 rPeptide
Beta-Amyloid (1-42), Ultra Pure, NaOH A-1165-2 rPeptide
品牌分类
β淀粉样抗体
Apolipoprotein/Apo
同核蛋白
头
淀粉样前体蛋白
by Disease
AD/PD相关蛋白
Alzheimer’s Products
标记肽&；蛋白质
Surfactants
标记钙调素蛋白
抗体
钙调素
载脂蛋白/载脂蛋白
Tau and Related proteins
Chemokine
Tubulin
新冠病毒-19/SARS-CoV-2相关；化合物
Labeled Calmodulin Proteins
β淀粉样蛋白标记肽，重组
β-淀粉样肽，人，天然和突变，重组
β淀粉样抗体
β淀粉样肽，人，天然和突变，重组
Covid-19/SARS-CoV-2 Related Kits
Parkinson’s Products
帕金森氏症产品
老年痴呆症产品
Covid-19/SARS-CoV-2相关；蛋白质
微管蛋白
新冠病毒-19/SARS-CoV-2相关；抗体
Synuclein
Beta-Amyloid Labeled Peptides, Synthetic
Synuclein
神经退行性变相关化合物
Amyloid Precursor Protein
Beta Amyloid Peptides
AD/PD相关蛋白
单克隆抗体
同核蛋白
表面活性剂
Covid-19 Research Tools
Proteins
Tau及其相关蛋白
钙调素
趋化因子
显示分类
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